Deep learning connects DNA traces to transcription to reveal predictive features beyond enhancer–promoter contact

Recent advances in super-resolution microscopy have made it possible to measure chromatin 3D structure and transcription in thousands of single cells. Here, authors present a deep learning-based approach to characterise how chromatin structure relates to transcriptional state of individual cells and...

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Autores principales: Aparna R. Rajpurkar, Leslie J. Mateo, Sedona E. Murphy, Alistair N. Boettiger
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6709defa5d6e4be39868c3cea25d7942
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