Transfer RNA-derived fragments in aging Caenorhabditis elegans originate from abundant homologous gene copies

Abstract Small RNAs that originate from transfer RNA (tRNA) species, tRNA-derived fragments (tRFs), play diverse biological functions but little is known for their association with aging. Moreover, biochemical aspects of tRNAs limit discovery of functional tRFs by high throughput sequencing. In part...

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Autores principales: GiWon Shin, Hee Jung Koo, Mihwa Seo, Seung-Jae V. Lee, Hong Gil Nam, Gyoo Yeol Jung
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/671708ab310442aba73295f37f88d034
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