Defects in the C. elegans acyl-CoA synthase, acs-3, and nuclear hormone receptor, nhr-25, cause sensitivity to distinct, but overlapping stresses.

Defects in the C. elegans acyl-CoA synthase, acs-3, and nuclear hormone receptor, nhr-25, cause sensitivity to distinct, but overlapping stresses.

Metazoan transcription factors control distinct networks of genes in specific tissues, yet understanding how these networks are integrated into physiology, development, and homeostasis remains challenging. Inactivation of the nuclear hormone receptor nhr-25 ameliorates developmental and metabolic ph...

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Auteurs principaux: Jordan D Ward, Brendan Mullaney, Benjamin J Schiller, Le D He, Sarah E Petnic, Carole Couillault, Nathalie Pujol, Teresita U Bernal, Marc R Van Gilst, Kaveh Ashrafi, Jonathan J Ewbank, Keith R Yamamoto
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/672348cb26964d8ab97c38820135c34d
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https://doaj.org/article/672348cb26964d8ab97c38820135c34d

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