Elucidating the mechanisms by which disulfiram protects against obesity and metabolic syndrome

Abstract There is an unmet need and urgency to find safe and effective anti-obesity interventions. Our recent study in mice fed on obesogenic diet found that treatment with the alcohol aversive drug disulfiram reduced feeding efficiency and led to a decrease in body weight and an increase in energy...

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Autores principales: Michel Bernier, Dylan Harney, Yen Chin Koay, Antonio Diaz, Abhishek Singh, Devin Wahl, Tamara Pulpitel, Ahmed Ali, Vince Guiterrez, Sarah J. Mitchell, Eun-Young Kim, John Mach, Nathan L. Price, Miguel A. Aon, David G. LeCouteur, Victoria C. Cogger, Carlos Fernandez-Hernando, John O’Sullivan, Mark Larance, Ana Maria Cuervo, Rafael de Cabo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/6764f6e5a0bd403f9dbc67a86fdcd3e6
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