Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25

Pfs25 is a transmission-blocking vaccine candidate for Plasmodium. Here, McLeod et al. analyze the antibody response to Pfs25 in sera from a clinical trial evaluating a Pfs25 vaccine candidate, identify a potent transmission-blocking antibody and determine recognized epitopes on Pfs25.

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Autores principales:	Brandon McLeod, Kazutoyo Miura, Stephen W. Scally, Alexandre Bosch, Ngan Nguyen, Hanjun Shin, Dongkyoon Kim, Wayne Volkmuth, Sebastian Rämisch, Jessica A. Chichester, Stephen Streatfield, Colleen Woods, William R. Schief, Daniel Emerling, C. Richter King, Jean-Philippe Julien
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/67758bcac9e4447fab4577c5f6b5c7a0
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spelling	oai:doaj.org-article:67758bcac9e4447fab4577c5f6b5c7a02021-12-02T14:38:59ZPotent antibody lineage against malaria transmission elicited by human vaccination with Pfs2510.1038/s41467-019-11980-62041-1723https://doaj.org/article/67758bcac9e4447fab4577c5f6b5c7a02019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11980-6https://doaj.org/toc/2041-1723Pfs25 is a transmission-blocking vaccine candidate for Plasmodium. Here, McLeod et al. analyze the antibody response to Pfs25 in sera from a clinical trial evaluating a Pfs25 vaccine candidate, identify a potent transmission-blocking antibody and determine recognized epitopes on Pfs25.Brandon McLeodKazutoyo MiuraStephen W. ScallyAlexandre BoschNgan NguyenHanjun ShinDongkyoon KimWayne VolkmuthSebastian RämischJessica A. ChichesterStephen StreatfieldColleen WoodsWilliam R. SchiefDaniel EmerlingC. Richter KingJean-Philippe JulienNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Brandon McLeod Kazutoyo Miura Stephen W. Scally Alexandre Bosch Ngan Nguyen Hanjun Shin Dongkyoon Kim Wayne Volkmuth Sebastian Rämisch Jessica A. Chichester Stephen Streatfield Colleen Woods William R. Schief Daniel Emerling C. Richter King Jean-Philippe Julien Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25
description	Pfs25 is a transmission-blocking vaccine candidate for Plasmodium. Here, McLeod et al. analyze the antibody response to Pfs25 in sera from a clinical trial evaluating a Pfs25 vaccine candidate, identify a potent transmission-blocking antibody and determine recognized epitopes on Pfs25.
format	article
author	Brandon McLeod Kazutoyo Miura Stephen W. Scally Alexandre Bosch Ngan Nguyen Hanjun Shin Dongkyoon Kim Wayne Volkmuth Sebastian Rämisch Jessica A. Chichester Stephen Streatfield Colleen Woods William R. Schief Daniel Emerling C. Richter King Jean-Philippe Julien
author_facet	Brandon McLeod Kazutoyo Miura Stephen W. Scally Alexandre Bosch Ngan Nguyen Hanjun Shin Dongkyoon Kim Wayne Volkmuth Sebastian Rämisch Jessica A. Chichester Stephen Streatfield Colleen Woods William R. Schief Daniel Emerling C. Richter King Jean-Philippe Julien
author_sort	Brandon McLeod
title	Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25
title_short	Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25
title_full	Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25
title_fullStr	Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25
title_full_unstemmed	Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25
title_sort	potent antibody lineage against malaria transmission elicited by human vaccination with pfs25
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/67758bcac9e4447fab4577c5f6b5c7a0
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_version_	1718390774888923136

Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25

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