Memantine inhibits α3β2-nAChRs-mediated nitrergic neurogenic vasodilation in porcine basilar arteries.

Memantine, an NMDA receptor antagonist used for treatment of Alzheimer's disease (AD), is known to block the nicotinic acetylcholine receptors (nAChRs) in the central nervous system (CNS). In the present study, we examined by wire myography if memantine inhibited α3β2-nAChRs located on cerebral...

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Autores principales: Reggie Hui-Chao Lee, Ting-Yi Tseng, Celeste Yin-Chieh Wu, Po-Yi Chen, Mei-Fang Chen, Jon-Son Kuo, Tony Jer-Fu Lee
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/6785d2e913f94094bc80a409e369fd61
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