Role of PKR and Type I IFNs in viral control during primary and secondary infection.

Type I interferons (IFNs) are known to mediate viral control, and also promote survival and expansion of virus-specific CD8+ T cells. However, it is unclear whether signaling cascades involved in eliciting these diverse cellular effects are also distinct. One of the best-characterized anti-viral sig...

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Autores principales: Yumi Nakayama, Erin H Plisch, Jeremy Sullivan, Chester Thomas, Charles J Czuprynski, Bryan R G Williams, M Suresh
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/67966041c01049d29b0c04ea45a7eb6e
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