Structural Analysis and Spatiotemporal Expression of <i>Atxn1</i> Genes in Zebrafish Embryos and Larvae

Zebrafish have come into focus to model cerebellar diseases such as spinocerebellar ataxias (SCAs), which is caused by an expansion of translated CAG repeats in several unrelated genes. In spinocerebellar ataxia type 1 (SCA1), gain-of-function in the mutant ATXN1 contributes to SCA1’s neuropathy. Hu...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Franz Vauti, Viktoria Vögele, Isabel Deppe, Susanne T. Hahnenstein, Reinhard W. Köster
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
SCA
Accès en ligne:https://doaj.org/article/67cb7b997c3047139be18c6bebeb2011
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!