Structural Analysis and Spatiotemporal Expression of <i>Atxn1</i> Genes in Zebrafish Embryos and Larvae
Zebrafish have come into focus to model cerebellar diseases such as spinocerebellar ataxias (SCAs), which is caused by an expansion of translated CAG repeats in several unrelated genes. In spinocerebellar ataxia type 1 (SCA1), gain-of-function in the mutant ATXN1 contributes to SCA1’s neuropathy. Hu...
Guardado en:
Autores principales: | Franz Vauti, Viktoria Vögele, Isabel Deppe, Susanne T. Hahnenstein, Reinhard W. Köster |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
MDPI AG
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/67cb7b997c3047139be18c6bebeb2011 |
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