Therapeutic Potential of Anti-Interferon α Vaccination on SjS-Related Features in the MRL/lpr Autoimmune Mouse Model

Therapeutic Potential of Anti-Interferon α Vaccination on SjS-Related Features in the MRL/lpr Autoimmune Mouse Model

Sjögren’s syndrome (SjS) is a frequent systemic autoimmune disease responsible for a major decrease in patients’ quality of life, potentially leading to life-threatening conditions while facing an unmet therapeutic need. Hence, we assessed the immunogenicity, efficacy, and tolerance of IFN-Kinoid (I...

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Autores principales: Martin Killian, Fabien Colaone, Philippe Haumont, Carole Nicco, Olivier Cerles, Sandrine Chouzenoux, Pascal Cathébras, Nicolas Rochereau, Blandine Chanut, Mireille Thomas, Norbert Laroche, Fabien Forest, Géraldine Grouard-Vogel, Frédéric Batteux, Stéphane Paul
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
Sjögren’s syndrome
vaccination
interferon a (IFN-a)
adjuvant
kinoid
Immunologic diseases. Allergy
RC581-607
Acceso en línea:https://doaj.org/article/67cc7f1960bc4cdea81c8665eade9db4
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https://doaj.org/article/67cc7f1960bc4cdea81c8665eade9db4

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