Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo

The molecular trigger that establishes cell polarity in the mammalian embryo is unclear. Here, the authors show that de novo polarisation of the mouse embryo at the 8-cell stage is directed by Phospholipase C and Protein kinase C and occurs in two phases: polarisation of actomyosin followed by the P...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Meng Zhu, Chuen Yan Leung, Marta N. Shahbazi, Magdalena Zernicka-Goetz
Format: article
Langue:EN
Publié: Nature Portfolio 2017
Sujets:
Q
Accès en ligne:https://doaj.org/article/67d03849c46c458394472948fa9b220e
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!