Characterizing the replicability of cell types defined by single cell RNA-sequencing data using MetaNeighbor
Single cell RNA-sequencing analysis poses challenges in replication due to technical biases and analytic variability among bioinformatics pipelines. Here, Crow et al develop MetaNeighbor for measuring cell-type replication across datasets, and use it to identify marker genes for neuron subtypes with...
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Main Authors: | Megan Crow, Anirban Paul, Sara Ballouz, Z. Josh Huang, Jesse Gillis |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Online Access: | https://doaj.org/article/67fefc8fb1054363be1ef3aa5f0f083c |
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