Insulin glargine: pharmacokinetic and pharmacodynamic basis of clinical effect

Glargine became the first long-acting insulin analogue. Glargine was designed to meet basal insulin requirements throughout the day with a single injection. Pharmacokinetics of insulin glargine is characterized by biotransformation into metabolites M1 and M2 that transforms the B chain of glargine s...

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Autores principales: Vadim Valer'evich Klimontov, Natalya Evgen'evna Myakina
Formato: article
Lenguaje:EN
RU
Publicado: Endocrinology Research Centre 2014
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Acceso en línea:https://doaj.org/article/68134155cb3a4de7b6012ca1ba4f09a4
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