Insulin glargine: pharmacokinetic and pharmacodynamic basis of clinical effect
Glargine became the first long-acting insulin analogue. Glargine was designed to meet basal insulin requirements throughout the day with a single injection. Pharmacokinetics of insulin glargine is characterized by biotransformation into metabolites M1 and M2 that transforms the B chain of glargine s...
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Main Authors: | Vadim Valer'evich Klimontov, Natalya Evgen'evna Myakina |
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Format: | article |
Language: | EN RU |
Published: |
Endocrinology Research Centre
2014
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Subjects: | |
Online Access: | https://doaj.org/article/68134155cb3a4de7b6012ca1ba4f09a4 |
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