Sterols lower energetic barriers of membrane bending and fission necessary for efficient clathrin-mediated endocytosis

Summary: Clathrin-mediated endocytosis (CME) is critical for cellular signal transduction, receptor recycling, and membrane homeostasis in mammalian cells. Acute depletion of cholesterol disrupts CME, motivating analysis of CME dynamics in the context of human disorders of cholesterol metabolism. We...

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Autores principales: Ruthellen H. Anderson, Kem A. Sochacki, Harika Vuppula, Brandon L. Scott, Elizabeth M. Bailey, Maycie M. Schultz, Jason G. Kerkvliet, Justin W. Taraska, Adam D. Hoppe, Kevin R. Francis
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/6823a6fdb1ef451ca0e218e688d63346
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