Predicting cancer drug TARGETS - TreAtment Response Generalized Elastic-neT Signatures

Abstract We are now in an era of molecular medicine, where specific DNA alterations can be used to identify patients who will respond to specific drugs. However, there are only a handful of clinically used predictive biomarkers in oncology. Herein, we describe an approach utilizing in vitro DNA and...

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Autores principales: Nicholas R. Rydzewski, Erik Peterson, Joshua M. Lang, Menggang Yu, S. Laura Chang, Martin Sjöström, Hamza Bakhtiar, Gefei Song, Kyle T. Helzer, Matthew L. Bootsma, William S. Chen, Raunak M. Shrestha, Meng Zhang, David A. Quigley, Rahul Aggarwal, Eric J. Small, Daniel R. Wahl, Felix Y. Feng, Shuang G. Zhao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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R
Acceso en línea:https://doaj.org/article/683460200e2546bd8518fb156fad7efa
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