Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation

The BubR1/Bub3 complex regulates chromosome segregation to enable proper kinetochore-microtubule interactions and is also required for the spindle assembly checkpoint. Here the authors show that two distinct pools of BubR1/Bub3 exist at kinetochores to support both known functions of BubR1/Bub3.

Guardado en:
Detalles Bibliográficos
Autores principales: Gang Zhang, Blanca Lopez Mendez, Garry G. Sedgwick, Jakob Nilsson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/683703f88b40405d9999b5a8529ec761
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!