Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation

The BubR1/Bub3 complex regulates chromosome segregation to enable proper kinetochore-microtubule interactions and is also required for the spindle assembly checkpoint. Here the authors show that two distinct pools of BubR1/Bub3 exist at kinetochores to support both known functions of BubR1/Bub3.

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Auteurs principaux: Gang Zhang, Blanca Lopez Mendez, Garry G. Sedgwick, Jakob Nilsson
Format: article
Langue:EN
Publié: Nature Portfolio 2016
Sujets:
Q
Accès en ligne:https://doaj.org/article/683703f88b40405d9999b5a8529ec761
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