pH-controlled stacking direction of the β-strands in peptide fibrils

Abstract Peptides provide a framework for generating functional biopolymers. In this study, the pH-dependent structural changes in the 21–29 fragment peptide of β2-microglobulin (β2m21–29) during self-aggregation, i.e., the formation of an amyloid fibril, were discussed. The β-sheet structures forme...

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Autores principales: Wei-Hsuan Tseng, Szu-Hua Chen, Hirotsugu Hiramatsu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/686b8df65ca945c899c8cea45c469a4f
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