IL-21 arming potentiates the anti-tumor activity of an oncolytic vaccinia virus in monotherapy and combination therapy

Background Oncolytic viruses (OVs) have shown promise in containing cancer progression in both animal models and clinical trials. How to further improve the efficacy of OVs are intensively explored. Arming OVs with immunoregulatory molecules has emerged as an important means to enhance their oncolyt...

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Autores principales: Xiaoyan Zhang, Chen Zhao, Tianyue Chen, Xiangqing Ding, Qibin Liao, Nan Gao, Jianqing Xu
Formato: article
Lenguaje:EN
Publicado: BMJ Publishing Group 2021
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Acceso en línea:https://doaj.org/article/687174a0e59c41bca53c7d8f25fba99b
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