Preclinical toxicological study of long-circulating and fusogenic liposomes co-encapsulating paclitaxel and doxorubicin in synergic ratio

Combination therapy between paclitaxel (PTX) and doxorubicin (DXR) is applied as the first-line treatment of breast cancer. Co-administration of drugs at synergistic ratio for treatment is facilitated with the use of nanocarriers, such as liposomes. However, despite the high response rate of solid t...

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Autores principales: Marjorie Coimbra Roque, Caroline Dohanik da Silva, Marthin Raboch Lempek, Geovanni Dantas Cassali, André Luís Branco de Barros, Marília Martins Melo, Mônica Cristina Oliveira
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/6877ad28e1be4f4dab58f15d3bd95e47
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