Kinesin-14 motors drive a right-handed helical motion of antiparallel microtubules around each other

Some kinesins exhibit off-axis power strokes but their impact on motility and force generation in microtubule overlaps has not been investigated so far. Here authors use a 3D in vitro motility assay and find that Ndc’s off-axis motor forces generate torque in antiparallel microtubules which causes m...

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Autores principales: Aniruddha Mitra, Laura Meißner, Rojapriyadharshini Gandhimathi, Roman Renger, Felix Ruhnow, Stefan Diez
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/689b9c88ea3c45eeb1fc9488aee2a4b3
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