A Critical Role for the Putative NCS2 Nucleobase Permease YjcD in the Sensitivity of <named-content content-type="genus-species">Escherichia coli</named-content> to Cytotoxic and Mutagenic Purine Analogs
ABSTRACT The base analogs 6-N-hydroxylaminopurine (HAP) and 2-amino-HAP (AHAP) are potent mutagens in bacteria and eukaryotic organisms. Previously, we demonstrated that a defect in the Escherichia coli ycbX gene, encoding a molybdenum cofactor-dependent oxidoreductase, dramatically enhances sensiti...
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| Auteurs principaux: | , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2013
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| Accès en ligne: | https://doaj.org/article/68a2d8d2cfe84970ba00000775f93822 |
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