Efficient double fragmentation ChIP-seq provides nucleotide resolution protein-DNA binding profiles.
Immunoprecipitated crosslinked protein-DNA fragments typically range in size from several hundred to several thousand base pairs, with a significant part of chromatin being much longer than the optimal length for next-generation sequencing (NGS) procedures. Because these larger fragments may be non-...
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Main Authors: | , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2010
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Online Access: | https://doaj.org/article/68b3e00bcb334a91b78ef370c1399ac7 |
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