Loop diuretics have anxiolytic effects in rat models of conditioned anxiety.

A number of antiepileptic medications that modulate GABA(A) mediated synaptic transmission are anxiolytic. The loop diuretics furosemide (Lasix) and bumetanide (Bumex) are thought to have antiepileptic properties. These drugs also modulate GABA(A) mediated signalling through their antagonism of cati...

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Autores principales: Andrew D Krystal, Janice Sutherland, Daryl W Hochman
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/690b3496b49341e2a3acaa3e98a2bfdd
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