A MATLAB-based program for three-dimensional quantitative analysis of micronuclei reveals that neuroinflammation induces micronuclei formation in the brain

Abstract The micronucleus is known to be a biomarker for genomic instability, which is a hallmark of tumors and aging. Normally, micronuclei are produced by segregation errors and mechanical stresses arising from dividing or migrating cells, leading to activation of the innate immune response pathwa...

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Autores principales: Sarasa Yano, Kaito Akiyama, Rio Tsuchiya, Hikari Kubotani, Tomoki Chiba, Takeshi Nagata, Fuminori Tsuruta
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/692244364ba24204a0d4329f4880b541
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