A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals
Biomarkers that predict mortality are of interest for clinical as well as research applications. Here, the authors analyze metabolomics data from 44,168 individuals and identify key metabolites independently associated with all-cause mortality risk.
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Nature Portfolio
2019
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oai:doaj.org-article:6923daf567204a5eb33b751c0974e1592021-12-02T17:02:17ZA metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals10.1038/s41467-019-11311-92041-1723https://doaj.org/article/6923daf567204a5eb33b751c0974e1592019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11311-9https://doaj.org/toc/2041-1723Biomarkers that predict mortality are of interest for clinical as well as research applications. Here, the authors analyze metabolomics data from 44,168 individuals and identify key metabolites independently associated with all-cause mortality risk.Joris DeelenJohannes KettunenKrista FischerAshley van der SpekStella TrompetGabi KastenmüllerAndy BoydJonas ZiererErik B. van den AkkerMika Ala-KorpelaNajaf AminAyse DemirkanMohsen GhanbariDiana van HeemstM. Arfan IkramJan Bert van KlinkenSimon P. MooijaartAnnette PetersVeikko SalomaaNaveed SattarTim D. SpectorHenning TiemeierAswin VerhoevenMelanie WaldenbergerPeter WürtzGeorge Davey SmithAndres MetspaluMarkus PerolaCristina MenniJohanna M. GeleijnseFotios DrenosMarian BeekmanJ. Wouter JukemaCornelia M. van DuijnP. Eline SlagboomNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-8 (2019) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Joris Deelen Johannes Kettunen Krista Fischer Ashley van der Spek Stella Trompet Gabi Kastenmüller Andy Boyd Jonas Zierer Erik B. van den Akker Mika Ala-Korpela Najaf Amin Ayse Demirkan Mohsen Ghanbari Diana van Heemst M. Arfan Ikram Jan Bert van Klinken Simon P. Mooijaart Annette Peters Veikko Salomaa Naveed Sattar Tim D. Spector Henning Tiemeier Aswin Verhoeven Melanie Waldenberger Peter Würtz George Davey Smith Andres Metspalu Markus Perola Cristina Menni Johanna M. Geleijnse Fotios Drenos Marian Beekman J. Wouter Jukema Cornelia M. van Duijn P. Eline Slagboom A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals |
| description |
Biomarkers that predict mortality are of interest for clinical as well as research applications. Here, the authors analyze metabolomics data from 44,168 individuals and identify key metabolites independently associated with all-cause mortality risk. |
| format |
article |
| author |
Joris Deelen Johannes Kettunen Krista Fischer Ashley van der Spek Stella Trompet Gabi Kastenmüller Andy Boyd Jonas Zierer Erik B. van den Akker Mika Ala-Korpela Najaf Amin Ayse Demirkan Mohsen Ghanbari Diana van Heemst M. Arfan Ikram Jan Bert van Klinken Simon P. Mooijaart Annette Peters Veikko Salomaa Naveed Sattar Tim D. Spector Henning Tiemeier Aswin Verhoeven Melanie Waldenberger Peter Würtz George Davey Smith Andres Metspalu Markus Perola Cristina Menni Johanna M. Geleijnse Fotios Drenos Marian Beekman J. Wouter Jukema Cornelia M. van Duijn P. Eline Slagboom |
| author_facet |
Joris Deelen Johannes Kettunen Krista Fischer Ashley van der Spek Stella Trompet Gabi Kastenmüller Andy Boyd Jonas Zierer Erik B. van den Akker Mika Ala-Korpela Najaf Amin Ayse Demirkan Mohsen Ghanbari Diana van Heemst M. Arfan Ikram Jan Bert van Klinken Simon P. Mooijaart Annette Peters Veikko Salomaa Naveed Sattar Tim D. Spector Henning Tiemeier Aswin Verhoeven Melanie Waldenberger Peter Würtz George Davey Smith Andres Metspalu Markus Perola Cristina Menni Johanna M. Geleijnse Fotios Drenos Marian Beekman J. Wouter Jukema Cornelia M. van Duijn P. Eline Slagboom |
| author_sort |
Joris Deelen |
| title |
A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals |
| title_short |
A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals |
| title_full |
A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals |
| title_fullStr |
A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals |
| title_full_unstemmed |
A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals |
| title_sort |
metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/6923daf567204a5eb33b751c0974e159 |
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