TNF induces glycolytic shift in fibroblast like synoviocytes via GLUT1 and HIF1A
Abstract TNF is a central cytokine in the pathogenesis of rheumatoid arthritis (RA). Elevated level of TNF causes local inflammation that affects immune cells and fibroblast-like synoviocytes (FLS). Nowadays, only 20–30% of patients experience remission after the standard of care therapy—antibodies...
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Autores principales: | , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/695dcc322f0344b397d04593c01b217c |
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