High concentration of extracellular nucleotides suppresses cell growth via delayed cell cycle progression in cancer and noncancer cell lines

Tumor necrosis frequently occurs in malignant tumors, showing rapid growth and invasion. This phenomenon is generally regarded as simple ischemic necrosis due to insufficient tumor vessels and blood supply. However, the necrotic tissue contains high amount of nuclear substances, DNA, and nucleoprote...

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Autores principales: Chika Sawa, Sachiko Yofu, Keisuke Kiriyama, Keita Sutoh, Tomomi Saito, Satomi Kishi, Mariko Gunji, Yuriko Inoue, Masahito Sugi, Seiji Shioda, Kazuho Honda
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/69b0aad5d1f44e999dba242fae3d6fdd
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