Associations between biomarkers of environmental enteric dysfunction and oral rotavirus vaccine immunogenicity in rural Zimbabwean infants

Background: Oral rotavirus vaccines (RVV) are poorly immunogenic in low-income countries. Environmental enteric dysfunction (EED) resulting from poor water, sanitation and hygiene (WASH) may contribute. We therefore tested associations between EED and RVV immunogenicity, and evaluated the effect of...

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Auteurs principaux:	James A Church, Sandra Rukobo, Margaret Govha, Ethan K Gough, Bernard Chasekwa, Benjamin Lee, Marya P Carmolli, Gordana Panic, Natasa Giallourou, Robert Ntozini, Kuda Mutasa, Monica M McNeal, Florence D. Majo, Naume V. Tavengwa, Jonathan R. Swann, Lawrence H Moulton, Beth D Kirkpatrick, Jean H Humphrey, Andrew J Prendergast
Format:	article
Langue:	EN
Publié:	Elsevier 2021
Sujets:	Infants Africa Rotavirus Oral vaccine Enteropathy Environmental enteric dysfunction Medicine (General) R5-920
Accès en ligne:	https://doaj.org/article/69cb5ba48b6d461b9a9af23e66c7c284
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Associations between biomarkers of environmental enteric dysfunction and oral rotavirus vaccine immunogenicity in rural Zimbabwean infants

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