The orthopedic characterization of cfap298 tm304 mutants validate zebrafish to faithfully model human AIS

Abstract Cerebrospinal fluid (CSF) circulation relies on the beating of motile cilia projecting in the lumen of the brain and spinal cord cavities Mutations in genes involved in cilia motility disturb cerebrospinal fluid circulation and result in scoliosis-like deformities of the spine in juvenile z...

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Autores principales: Marie-Hardy Laura, Cantaut-Belarif Yasmine, Pietton Raphaël, Slimani Lotfi, Pascal-Moussellard Hugues
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/69e0796306d143ba9630ebf9418ce8bb
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