Causal effects of atrial fibrillation on brain white and gray matter volume: a Mendelian randomization study

Causal effects of atrial fibrillation on brain white and gray matter volume: a Mendelian randomization study

Abstract Background Atrial fibrillation (AF) and brain volume loss are prevalent in older individuals. We aimed to assess the causal effect of atrial fibrillation on brain volume phenotypes by Mendelian randomization (MR) analysis. Methods The genetic instrument for AF was constructed from a previou...

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Bibliographic Details
Main Authors: Sehoon Park, Soojin Lee, Yaerim Kim, Semin Cho, Kwangsoo Kim, Yong Chul Kim, Seung Seok Han, Hajeong Lee, Jung Pyo Lee, Soryoung Lee, Eue-Keun Choi, Kwon Wook Joo, Chun Soo Lim, Yon Su Kim, Dong Ki Kim
Format: article
Language:EN
Published: BMC 2021
Subjects:
Atrial fibrillation
Brain
Stroke
Mendelian randomization
Medicine
R
Online Access:https://doaj.org/article/69e75ddb2e9149c98c4241c87dc7fd73
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