Reproductive fitness and genetic risk of psychiatric disorders in the general population

Reproductive fitness and genetic risk of psychiatric disorders in the general population

Why genetic variants that confer risk for psychiatric disorders persist in the genome is an evolutionary conundrum. Here, Mullinset al. report association of polygenic risk for autism with having fewer children and polygenic risk for ADHD with higher reproductive fitness.

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Autores principales: Niamh Mullins, Andrés Ingason, Heather Porter, Jack Euesden, Alexandra Gillett, Sigurgeir Ólafsson, Daniel F. Gudbjartsson, Cathryn M. Lewis, Engilbert Sigurdsson, Evald Saemundsen, Ólafur Ó Gudmundsson, Michael L. Frigge, Augustine Kong, Agnar Helgason, G. Bragi Walters, Omar Gustafsson, Hreinn Stefansson, Kari Stefansson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/6a60e54dd24e47ccb00660d46b48e9ad
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https://doaj.org/article/6a60e54dd24e47ccb00660d46b48e9ad

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