Reproductive fitness and genetic risk of psychiatric disorders in the general population

Why genetic variants that confer risk for psychiatric disorders persist in the genome is an evolutionary conundrum. Here, Mullinset al. report association of polygenic risk for autism with having fewer children and polygenic risk for ADHD with higher reproductive fitness.

Saved in:
Bibliographic Details
Main Authors: Niamh Mullins, Andrés Ingason, Heather Porter, Jack Euesden, Alexandra Gillett, Sigurgeir Ólafsson, Daniel F. Gudbjartsson, Cathryn M. Lewis, Engilbert Sigurdsson, Evald Saemundsen, Ólafur Ó Gudmundsson, Michael L. Frigge, Augustine Kong, Agnar Helgason, G. Bragi Walters, Omar Gustafsson, Hreinn Stefansson, Kari Stefansson
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Q
Online Access:https://doaj.org/article/6a60e54dd24e47ccb00660d46b48e9ad
Tags: Add Tag
No Tags, Be the first to tag this record!