rAAV-mediated overexpression of TGF-β via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model

rAAV-mediated overexpression of TGF-β via vector delivery in polymeric micelles stimulates the biological and reparative activities of human articular chondrocytes in vitro and in a human osteochondral defect model

Ana Rey-Rico,1 Jagadeesh K Venkatesan,1 Gertrud Schmitt,1 Angel Concheiro,2 Henning Madry,1,3 Carmen Alvarez-Lorenzo,2 Magali Cucchiarini1 1Center of Experimental Orthopedics, Saarland University Medical Center, Homburg, Germany; 2Department of Pharmacology, Pharmacy and Pharmaceutical Technology,...

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Autores principales: Rey-Rico A, Venkatesan JK, Schmitt G, Concheiro A, Madry H, Alvarez-Lorenzo C, Cucchiarini M
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2017
Materias:
human articular cartilage
rAAV gene transfer
TGF-
poloxamer
poloxamine.
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/6a67142a90284a1d95957030f0050421
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https://doaj.org/article/6a67142a90284a1d95957030f0050421

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