Circadian timekeeping is disturbed in rheumatoid arthritis at molecular level.

<h4>Introduction</h4>Patients with rheumatoid arthritis (RA) have disturbances in the hypothalamic-pituitary-adrenal (HPA) axis. These are reflected in altered circadian rhythm of circulating serum cortisol, melatonin and IL-6 levels and in chronic fatigue. We hypothesized that the molec...

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Autores principales: Vesa-Petteri Kouri, Juri Olkkonen, Emilia Kaivosoja, Mari Ainola, Juuso Juhila, Iiris Hovatta, Yrjö T Konttinen, Jami Mandelin
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/6a82eb79d24f4cc980665e0d9b1e4821
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