Chemotherapy confers a conserved secondary tolerance to EGFR inhibition via AXL-mediated signaling bypass
Abstract Drug resistance remains the major culprit of therapy failure in disseminated cancers. Simultaneous resistance to multiple, chemically different drugs feeds this failure resulting in cancer relapse. Here, we investigate co-resistance signatures shared between antimitotic drugs (AMDs) and inh...
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Autores principales: | , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/6a9ce31adb9b43ee90c928b9bc9e7e9b |
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