Chemotherapy confers a conserved secondary tolerance to EGFR inhibition via AXL-mediated signaling bypass

Abstract Drug resistance remains the major culprit of therapy failure in disseminated cancers. Simultaneous resistance to multiple, chemically different drugs feeds this failure resulting in cancer relapse. Here, we investigate co-resistance signatures shared between antimitotic drugs (AMDs) and inh...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Mark Borris D. Aldonza, Roben D. Delos Reyes, Young Seo Kim, Jayoung Ku, Ana Melisa Barsallo, Ji-Young Hong, Sang Kook Lee, Han Suk Ryu, YongKeun Park, Je-Yoel Cho, Yoosik Kim
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/6a9ce31adb9b43ee90c928b9bc9e7e9b
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!