Transportan 10 improves the pharmacokinetics and pharmacodynamics of vancomycin

Abstract In the presented study, transportan 10 (TP10), an amphipathic cell penetrating peptide (CPP) with high translocation activity, was conjugated with vancomycin (Van), which is known for poor access to the intracellular bacteria and the brain. The antibacterial activity of the conjugates was t...

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Bibliographic Details
Main Authors: Jarosław Ruczyński, Izabela Rusiecka, Katarzyna Turecka, Agnieszka Kozłowska, Magdalena Alenowicz, Iwona Gągało, Anna Kawiak, Piotr Rekowski, Krzysztof Waleron, Ivan Kocić
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
R
Q
Online Access:https://doaj.org/article/6ab41cdc1a11452badeea81901679a26
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