Transportan 10 improves the pharmacokinetics and pharmacodynamics of vancomycin
Abstract In the presented study, transportan 10 (TP10), an amphipathic cell penetrating peptide (CPP) with high translocation activity, was conjugated with vancomycin (Van), which is known for poor access to the intracellular bacteria and the brain. The antibacterial activity of the conjugates was t...
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Autores principales: | Jarosław Ruczyński, Izabela Rusiecka, Katarzyna Turecka, Agnieszka Kozłowska, Magdalena Alenowicz, Iwona Gągało, Anna Kawiak, Piotr Rekowski, Krzysztof Waleron, Ivan Kocić |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/6ab41cdc1a11452badeea81901679a26 |
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