Protective effect of dexmedetomidine in cecal ligation perforation-induced acute lung injury through HMGB1/RAGE pathway regulation and pyroptosis activation

Protective effect of dexmedetomidine in cecal ligation perforation-induced acute lung injury through HMGB1/RAGE pathway regulation and pyroptosis activation

Sepsis remains a major cause of mortality and morbidity in intensive care units. Dexmedetomidine (DEX) has been reported to attenuate cecal ligation perforation (CLP)-stimulated acute lung injury (ALI) by downregulating high-mobility group protein 1 (HMGB1) and receptor for advanced glycation end pr...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Huaqin Sun, Hongyi Hu, Xiaoping Xu, Mingsun Fang, Tao Tao, Zhehao Liang
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2021
Materias:
dexmedetomidine
acute lung injury
hmgb1
rage
nf-κb
pyroptosis
Biotechnology
TP248.13-248.65
Acceso en línea:https://doaj.org/article/6ac67c1f8d094b458a6af15a2e0a6b7e
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Internet

https://doaj.org/article/6ac67c1f8d094b458a6af15a2e0a6b7e

Ejemplares similares