Regional differences in susceptibiity of bronchial epithelium to mesenchymal transition and inhibition by the macrolide antibiotic azithromycin.

<h4>Objective</h4>Dysregulated repair following epithelial injury is a key forerunner of disease in many organs, and the acquisition of a mesenchymal phenotype by the injured epithelial cells (epithelial to mesenchymal transition, EMT) may serve as a source of fibrosis. The macrolide ant...

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Auteurs principaux: Balarka Banerjee, Michael Musk, Erika N Sutanto, Stephanie T Yerkovich, Peter Hopkins, Darryl A Knight, Suzanna Lindsey-Temple, Stephen M Stick, Anthony Kicic, Daniel C Chambers
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/6aeeacc9ffd64d5392193b4765bf2bf6
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