Antimycobacterial and anticancer activity of newly designed cinnamic acid hydrazides with favorable toxicity profile

A series of twelve novel hybrids of cinnamic acid and thiocarbohydrazones were designed, synthesized in high yield using a simple coupling strategy via acid chlorides, and evaluated for their impact against Mycobacterium tuberculosis (Mtb) and cancer cells survival. Among them, compound 3 demonstrat...

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Bibliographic Details
Main Authors: Mohamed H. Assaleh, Snezana K. Bjelogrlic, Nevena Prlainovic, Ilija Cvijetic, Aleksandra Bozic, Irena Arandjelovic, Dragana Vukovic, Aleksandar Marinkovic
Format: article
Language:EN
Published: Elsevier 2022
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Online Access:https://doaj.org/article/6b03d804b615461e9396edd3aa2fc120
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