Structure network-based landscape of rhodopsin misfolding by mutations and algorithmic prediction of small chaperone action

Failure of a protein to achieve its functional structural state and normal cellular location contributes to the etiology and pathology of heritable human conformational diseases. The autosomal dominant form of retinitis pigmentosa (adRP) is an incurable blindness largely linked to mutations of the m...

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Bibliographic Details
Main Authors: Angelo Felline, Davide Schiroli, Antonella Comitato, Valeria Marigo, Francesca Fanelli
Format: article
Language:EN
Published: Elsevier 2021
Subjects:
Online Access:https://doaj.org/article/6b05cf102d514fdb81a8be978d6899c1
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