Structure network-based landscape of rhodopsin misfolding by mutations and algorithmic prediction of small chaperone action

Failure of a protein to achieve its functional structural state and normal cellular location contributes to the etiology and pathology of heritable human conformational diseases. The autosomal dominant form of retinitis pigmentosa (adRP) is an incurable blindness largely linked to mutations of the m...

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Autores principales: Angelo Felline, Davide Schiroli, Antonella Comitato, Valeria Marigo, Francesca Fanelli
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/6b05cf102d514fdb81a8be978d6899c1
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