Design, Synthesis, In Vitro Anticancer Evaluation and Molecular Modelling Studies of 3,4,5-Trimethoxyphenyl-Based Derivatives as Dual EGFR/HDAC Hybrid Inhibitors

Recently, combining histone deacetylase (HDAC) inhibitors with chemotherapeutic drugs or agents, in particular epidermal growth factor receptor (EGFR) inhibitors, is considered to be one of the most encouraging strategy to enhance the efficacy of the antineoplastic agents and decrease or avoid drug...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Tarek S. Ibrahim, Azizah M. Malebari, Mamdouh F. A. Mohamed
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
R
Accès en ligne:https://doaj.org/article/6b1935634bf64310b98e1acf2ad5f1f6
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!