Genetic architecture of host proteins involved in SARS-CoV-2 infection

Finding effective treatments for COVID-19 depends upon understanding genetic regulation of proteins involved in SARS-CoV-2 infection and host response. Here, the authors identify genetic variants linked to expression of such proteins, data which could lead to the discovery of therapeutic targets.

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Auteurs principaux: Maik Pietzner, Eleanor Wheeler, Julia Carrasco-Zanini, Johannes Raffler, Nicola D. Kerrison, Erin Oerton, Victoria P. W. Auyeung, Jian’an Luan, Chris Finan, Juan P. Casas, Rachel Ostroff, Steve A. Williams, Gabi Kastenmüller, Markus Ralser, Eric R. Gamazon, Nicholas J. Wareham, Aroon D. Hingorani, Claudia Langenberg
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/6b38e315ccef41ffb7a303ba54fecf8c
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