Genetic architecture of host proteins involved in SARS-CoV-2 infection

Finding effective treatments for COVID-19 depends upon understanding genetic regulation of proteins involved in SARS-CoV-2 infection and host response. Here, the authors identify genetic variants linked to expression of such proteins, data which could lead to the discovery of therapeutic targets.

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Autores principales:	Maik Pietzner, Eleanor Wheeler, Julia Carrasco-Zanini, Johannes Raffler, Nicola D. Kerrison, Erin Oerton, Victoria P. W. Auyeung, Jian’an Luan, Chris Finan, Juan P. Casas, Rachel Ostroff, Steve A. Williams, Gabi Kastenmüller, Markus Ralser, Eric R. Gamazon, Nicholas J. Wareham, Aroon D. Hingorani, Claudia Langenberg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6b38e315ccef41ffb7a303ba54fecf8c
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spelling	oai:doaj.org-article:6b38e315ccef41ffb7a303ba54fecf8c2021-12-02T13:57:22ZGenetic architecture of host proteins involved in SARS-CoV-2 infection10.1038/s41467-020-19996-z2041-1723https://doaj.org/article/6b38e315ccef41ffb7a303ba54fecf8c2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19996-zhttps://doaj.org/toc/2041-1723Finding effective treatments for COVID-19 depends upon understanding genetic regulation of proteins involved in SARS-CoV-2 infection and host response. Here, the authors identify genetic variants linked to expression of such proteins, data which could lead to the discovery of therapeutic targets.Maik PietznerEleanor WheelerJulia Carrasco-ZaniniJohannes RafflerNicola D. KerrisonErin OertonVictoria P. W. AuyeungJian’an LuanChris FinanJuan P. CasasRachel OstroffSteve A. WilliamsGabi KastenmüllerMarkus RalserEric R. GamazonNicholas J. WarehamAroon D. HingoraniClaudia LangenbergNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maik Pietzner Eleanor Wheeler Julia Carrasco-Zanini Johannes Raffler Nicola D. Kerrison Erin Oerton Victoria P. W. Auyeung Jian’an Luan Chris Finan Juan P. Casas Rachel Ostroff Steve A. Williams Gabi Kastenmüller Markus Ralser Eric R. Gamazon Nicholas J. Wareham Aroon D. Hingorani Claudia Langenberg Genetic architecture of host proteins involved in SARS-CoV-2 infection
description	Finding effective treatments for COVID-19 depends upon understanding genetic regulation of proteins involved in SARS-CoV-2 infection and host response. Here, the authors identify genetic variants linked to expression of such proteins, data which could lead to the discovery of therapeutic targets.
format	article
author	Maik Pietzner Eleanor Wheeler Julia Carrasco-Zanini Johannes Raffler Nicola D. Kerrison Erin Oerton Victoria P. W. Auyeung Jian’an Luan Chris Finan Juan P. Casas Rachel Ostroff Steve A. Williams Gabi Kastenmüller Markus Ralser Eric R. Gamazon Nicholas J. Wareham Aroon D. Hingorani Claudia Langenberg
author_facet	Maik Pietzner Eleanor Wheeler Julia Carrasco-Zanini Johannes Raffler Nicola D. Kerrison Erin Oerton Victoria P. W. Auyeung Jian’an Luan Chris Finan Juan P. Casas Rachel Ostroff Steve A. Williams Gabi Kastenmüller Markus Ralser Eric R. Gamazon Nicholas J. Wareham Aroon D. Hingorani Claudia Langenberg
author_sort	Maik Pietzner
title	Genetic architecture of host proteins involved in SARS-CoV-2 infection
title_short	Genetic architecture of host proteins involved in SARS-CoV-2 infection
title_full	Genetic architecture of host proteins involved in SARS-CoV-2 infection
title_fullStr	Genetic architecture of host proteins involved in SARS-CoV-2 infection
title_full_unstemmed	Genetic architecture of host proteins involved in SARS-CoV-2 infection
title_sort	genetic architecture of host proteins involved in sars-cov-2 infection
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6b38e315ccef41ffb7a303ba54fecf8c
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Genetic architecture of host proteins involved in SARS-CoV-2 infection

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