Application of LDH assay for therapeutic efficacy evaluation of ex vivo tumor models

Abstract The current standard preclinical oncology models are not able to fully recapitulate therapeutic targets and clinically relevant disease biology, evidenced by the 90% attrition rate of new therapies in clinical trials. Three-dimensional (3D) culture systems have the potential to enhance the...

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Main Authors: Megan C. Cox, Rita Mendes, Fernanda Silva, Teresa F. Mendes, Adelyn Zelaya-Lazo, Kathleen Halwachs, Julie J. Purkal, Inês A. Isidro, Ana Félix, Erwin R. Boghaert, Catarina Brito
Format: article
Language:EN
Published: Nature Portfolio 2021
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R
Q
Online Access:https://doaj.org/article/6ba6021cf4734f4ebc89722a5ae55c02
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