Alterations in the inflammatory cytokines and brain-derived neurotrophic factor contribute to depression-like phenotype after spared nerve injury: improvement by ketamine

Alterations in the inflammatory cytokines and brain-derived neurotrophic factor contribute to depression-like phenotype after spared nerve injury: improvement by ketamine

Abstract Although pain is frequently accompanied with depression, little is known about the risk factors contributing to individual differences to the comorbidity of pain and depression. In this study, we examined whether cytokines and brain-derived neurotrophic factor (BDNF) might contribute to the...

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Bibliographic Details
Main Authors: Ze-Min Xie, Xing-Ming Wang, Ning Xu, Jing Wang, Wei Pan, Xiao-Hui Tang, Zhi-Qiang Zhou, Kenji Hashimoto, Jian-Jun Yang
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/6bafc4b7327e4bd8b849fe0411c5c977
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