Perturbing the Normal Level of SIDT1 Suppresses the Naked ASO Effect
Although antisense oligonucleotide (ASO) therapeutics can be taken up by living cells without carrier molecules, a large part of incorporated ASOs are trapped in the endosomes and do not exert therapeutic effects. To improve their therapeutic effects, it would be important to elucidate the mechanism...
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| Auteurs principaux: | , , , |
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| Format: | article |
| Langue: | EN |
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Hindawi Limited
2021
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| Accès en ligne: | https://doaj.org/article/6bbd43e111d942ffb5f9e3594e13f4dc |
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